@article {562986, title = {Comment on "Drosophila dosage compensation involves enhanced Pol II recruitment to male X-linked promoters".}, journal = {Science}, volume = {340}, number = {6130}, year = {2013}, month = {2013 Apr 19}, pages = {273}, abstract = { Conrad et al. (Reports, 10 August 2012, p. 742) reported a doubling of RNA polymerase II (Pol II) occupancy at X-linked promoters to support 5{\textquoteright} recruitment as the key mechanism for dosage compensation in Drosophila. However, they employed an erroneous data-processing step, overestimating Pol II differences. Reanalysis of the data fails to support the authors{\textquoteright} model for dosage compensation. }, keywords = {Animals, DNA Polymerase II, Dosage Compensation, Genetic, Drosophila, Drosophila Proteins, Female, Genes, X-Linked, Male, Promoter Regions, Genetic, X Chromosome}, issn = {1095-9203}, doi = {10.1126/science.1231815}, author = {Ferrari, F* and Jung, Y L* and Kharchenko, P V and Plachetka, A and Alekseyenko, A A and Kuroda, M I and Park, P J} }