@article {1638815, title = {The 4D Nucleome Data Portal as a resource for searching and visualizing curated nucleomics data}, journal = {Nature Communications}, volume = {13}, number = {1}, year = {2022}, month = {2022 May 02}, pages = {2365}, abstract = {The 4D Nucleome (4DN) Network aims to elucidate the complex structure and organization of chromosomes in the nucleus and the impact of their disruption in disease biology. We present the 4DN Data Portal ( https://data.4dnucleome.org/ ), a repository for datasets generated in the 4DN network and relevant external datasets. Datasets were generated with a wide range of experiments, including chromosome conformation capture assays such as Hi-C and other innovative sequencing and microscopy-based assays probing chromosome architecture. All together, the 4DN data portal hosts more than 1800 experiment sets and 36000 files. Results of sequencing-based assays from different laboratories are uniformly processed and quality-controlled. The portal interface allows easy browsing, filtering, and bulk downloads, and the integrated HiGlass genome browser allows interactive visualization and comparison of multiple datasets. The 4DN data portal represents a primary resource for chromosome contact and other nuclear architecture data for the scientific community.}, issn = {2041-1723}, doi = {10.1038/s41467-022-29697-4}, author = {Reiff, Sarah B and Schroeder, Andrew J and K{\i}rl{\i}, Koray and Cosolo, Andrea and Bakker, Clara and Mercado, Luisa and Lee, Soohyun and Veit, Alexander D and Balashov, Alexander K and Vitzthum, Carl and Ronchetti, William and Pitman, Kent M and Johnson, Jeremy and Ehmsen, Shannon R and Kerpedjiev, Peter and Abdennur, Nezar and Imakaev, Maxim and {\"O}zt{\"u}rk, Serkan Utku and {\c C}amo{\u g}lu, U{\u g}ur and Mirny, Leonid A and Gehlenborg, N* and Alver, Burak H* and Park, Peter J*} }