@article {153111,
	title = {Human decidual natural killer cells are a unique NK cell subset with immunomodulatory potential.},
	journal = {J Exp Med},
	volume = {198},
	number = {8},
	year = {2003},
	month = {2003 Oct 20},
	pages = {1201-12},
	abstract = {
	Natural killer cells constitute 50-90\% of lymphocytes in human uterine decidua in early pregnancy. Here, CD56(bright) uterine decidual NK (dNK) cells were compared with the CD56(bright) and CD56(dim) peripheral NK cell subsets by microarray analysis, with verification of results by flow cytometry and RT-PCR. Among the approximately 10,000 genes studied, 278 genes showed at least a threefold change with P \&lt; or = 0.001 when comparing the dNK and peripheral NK cell subsets, most displaying increased expression in dNK cells. The largest number of these encoded surface proteins, including the unusual lectinlike receptors NKG2E and Ly-49L, several killer cell Ig-like receptors, the integrin subunits alpha(D), alpha(X), beta1, and beta5, and multiple tetraspanins (CD9, CD151, CD53, CD63, and TSPAN-5). Additionally, two secreted proteins, galectin-1 and progestagen-associated protein 14, known to have immunomodulatory functions, were selectively expressed in dNK cells.

},
	keywords = {Antigens, CD56, Decidua, Female, Galectin 1, Gene Expression, Glycoproteins, Homeodomain Proteins, Humans, Killer Cells, Natural, NK Cell Lectin-Like Receptor Subfamily C, Oligonucleotide Array Sequence Analysis, Pregnancy, Pregnancy Proteins, Receptors, Immunologic, Receptors, Natural Killer Cell, T-Lymphocyte Subsets},
	issn = {0022-1007},
	doi = {10.1084/jem.20030305},
	author = {Koopman, Louise A and Kopcow, Hernan D and Rybalov, Basya and Boyson, Jonathan E and Orange, Jordan S and Schatz, Frederick and Masch, Rachel and Lockwood, Charles J and Schachter, Asher D and <b>Park, Peter J</b> and Strominger, Jack L}
}
